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New Anti-Fungal Antimicrobial Index supported by PediMD


The Antimicrobial Index is a reference tool designed to primarily serve and enrich the work of microboilogists, cellbiologists, life-science professionals, and the worldwide scientific community. Currently, the index contains both susceptibility and potency data for thousands of microorganisms, anti-fungal oils and extracts, and antimicrobial agents. 

The database seeks to not only raise consciousness regarding rising antimicrobial resistances such as Anti-fungal pills, but also to provide a comprehensive reference tool for microbiologists and other life-science professionals to use.

anti fungal microbial anti fungal index

The database includes over 33,000 Microorganisms, 4,400 Strains, 1,150 Antimicrobials and 800 Papers!

The Antimicrobial Index can be used for:

  • Discovering new antimicrobials 
  • Cross-referencing antimicrobial potencies 
  • Finding the most effective antimicrobial for your needs 
  • Locating literature relevant to your research

The online version of The Antimicrobial Index allows users to cross-reference literature-based susceptibility data with hundreds of antibiotics, thus allowing for more informed and efficient use of antimicrobials. 

Using the index is as easy as entering the name of any antimicrobial, antibiotic, anti-fungal, antiviral, antiparasitic agent or microorganism and clicking the search button to browse minimum inhibitory concentration (MIC) data. If you are interested in a specific microorganism, you can learn more about which antimicrobial agent can most effectively inhibit the growth of the microorganism by browsing the database (you may be surprised!).


Toenail Fungus Treatments: Including Sporanox and Lamisil Reviews


Fungaled toenails, or onychomycosis, can be unsightly and lead to ingrown toenails due to increased nail thickness, cracking and peelng skin. In general, doctors tend to stay away from prescribing  oral anti-fungal medicine, such as Sporanox and lamisil anti-fungal pills, due to their negative side-effects on the liver.

IOnychomycosis2t can take up to a year to notice a considerable difference with any treatment. For those of you willing to undertake the task of attacking toenail fungus, here are your weapons.

What kills fungus?

Air, vinegar, bleach, tea tree oil, and dryness are a few of the weapons we can easily combine to kill fungus. Fungus lives in moist areas such as sweaty socks, shower stalls and shoe linings. Fungus thrives in an anaerobic (oxygen deprived) environment under the nail called the Nail Matrix. Treating the Nail Matrix will eliminate the source of the fungus and eventually allow a new healthy nail to grow out.

Tactics to Eliminate Toenail Fungus


Get as much air under the nails by cutting the nails as short as possible, gently cleaning the debri under the nails, using an emery board weekly to file the top of the nails, and avoiding toe nail polish as much as possible (quickly remove when not needed).


Soak your feet in white vinegar 30 minutes twice weekly using a 1 part warm water to 1 part white vinegar ratio. 


Disinfect your shower weekly with bleach (ie Lysol).


Apply daily tea tree oil twenty minutes before you go to bed to each affected nail. It must dry well before getting under the sheets. 


Air out your shoes weekly that you use regularly by removing the shoe inserts, applying foot powder under and on top of any insert, and rubbing at the top of the toebox where you imagine the toenails rub.


One problem we have conquering toenail fungus is time. It takes over one year for the toenail to completely grow out twice. There is a general rule that it takes not one, but two of these growth spurts to push the unsightly debri of the killed fungus out from under the nail bed

If you decide to use oral anti-fungal pills, it is recommended to use pulsed Sporanox. It is the safest on the market. The treatment consists of taking Sporanox Pills for 7 days each month for 6 months. You still have to do the topical treatments as mentioned above. At present, the pulsed Sporonox does not need liver testing as part of the treatment, but your prescribing doctor may feel safer doing that. Golden Rule of Foot: Always err on the side of caution.

(Excerpt from Dr. Richard Blake's Article "Toenail Fungus: Key Points of Treatment")

Doctor Recommended: The PediMD Solution

toenail fungus treatment

Sporanox and Lamisil Anti-Fungal Pills are a short-term fix


Sporanox and Lamisil Fungal Nail Pills Are A Short Term Fix

Sporanox and Lamisil Fungal Pills are among the newest advancements in the treatment of nail fungus. Both Lamilisl Pills and Sporanox Pills have been on the market for years and have become a consideration when deciding to treat fungus. The only question is how long do they work for and are they worth the money and health risk's.

Lamisil and Sporonox Pills Lamisil and Sporanox Pills treat fungus by sitting in the nail root, also known as the matrix, and clearing the fungus in the matrix. The nail matrix is where nail matter is produced and as the fungus in the nail matrix is cleared the new nail grows out fungus free. Lamisil and Sporoanox Pills will only temporarily clear the matrix of the nail. The shortcoming for this treatment is after treatment, when the nails are once again suseptable to getting fungus. In other words as soon as the Lamisil or Sporanox medication leaves  your system and the nail matrix, the fungus returns.

Lamisil and Sporanox Fungal Pills: How They Work

  1. Begin Eating Pill
  2. Pills Enters System
  3. Pills Sits in Nail Matrix and Clears Matrix
  4. Nail Begins to Grow Out Clear
  5. Some of Medication is Cleared Through Liver
  6. Medication Leaves System
  7. Fungus May Return to Unprotected Nail and Matrix

Problems with Anti-Fungal Pills

  1. Very Expensive - Cost about $800, may be covered by insurance 
  2. Damage Liver - Perscription is often accompanied by frequent blood tests to ensure that the liver is safe. Doctors recommend that patients do not consume Alcohol or smoke when taking pills
  3. High Chance that Fungus will Return - After treatment the nail matrix is suseptable to contract fungus again

Two new advances in the treatment of nail fungus are nail laser therapy and advanced nail lacquers. Both of these treatments have had excellent outcomes and do not have the risks of liver irritation or damage associated with the fungal pills. The best option we have found is combining the nail laser and lacquer together.

Advantages of Nail Laser:

  • No pain: In office procedure
  • Clears Fungus: Treats both Nail and Matrix to
  • Quick Treatmet: Only One or Two Treatments
  • Does not harm body: liver stays intact

Advantages of Nail Lacquer:

  • No pain 
  • Fairly Inexpensive; Should not cost more than $30 for treatment  
  • Treats both Nail and Matrix 
  • No side effects  
  • Continued Nail protection:Apply lacquer once a week to prevent fungus from returning

The Doctors Recommendation

What I believe is the best treatment option is simple. Use either the pill, if your insurance will cover the costs and and you are okay with the risks of liver irritation. Or use the laser if you can afford it as insurance does not cover it. Whichever treatment option you prefer, make sure to combine a nail lacquer with the treatment and when the nail is clear, use an Anti-fungal nail lacquer that can offer long term protection to prevent the nail from getting re-infected.

Nail lacquer PediMDPediMD Antifungal Nail Treatment System has been designed for this specific purpose. It is an excellent treatment system for nail fungus and can also be combined with anti-fungal pills or fungus laser treatment. PediMD offers a second attack to the nail fungus. The best part is that the nail lacquer helps protect the nail while taking the pills or during laser treatment.

Related Article:

Ultimate Anti-Fungal Approach: Combining Laser and Lacquer

Common Nail Fungus Cures: What works and what does not


There are so many choices for nail fungus treatment and not all of them work. Even those that do work do not always continue to work when they are stopped. This article explains options and what I believe to be the best choices.

1: Antifungal Pills : Lamasil and Sporanox

These work about 70% of the time. They clear the nail but once they are stopped, the nail fungus can return as the nail is no longer protected. They also can upset or damage the liver and have many side effects. Make sure to check blood work prior to starting and after one month of use. Nail clearing will take about 6 months to one year. Protect the nail after it is clear with a protective nail anti fungal lacquer.

2: Fungus nail laser

fungal laser

This has been shown to work in very small tests. It is very new and very expensive and not covered by insurance. The jury is stil lout on if it works and how well. It seems to require more than one treatment and once it is stopped, the nail is not protected. No side effect associated with laser treatment except for occasional but rare skin irritation if not done properly. Make sure to follow up with a protective nail anti fungal lacquer after treatment to prevent fungus return.

3: Gel or liquid nail treatments

These just don’t work. The gel type is usually vaseline based and smears everywhere. It is hard to keep on the nail and rubs off. If it is not on the nail it cannot treat the fungus. More importantly, if it does not penetrate into the nail, which it can’t, it will not treat the fungus. The liquid kind is worse. It just rolls off the nail and so is really not effective.

4: Home remedies

Most home remedies are one of the ingredients in other forms of fungal treatments. For example, Vick’s Vapo rub is vaseline and menthol based. Menthol has been okay for fungal treatments but again the vaseline is hard to use and messy.Vinegar is a strong anti fungal but needs to used as a soak for hours and can dry the skin badly. In general, home remedies are poor choices as they all lack something andhave side effects or can irritate just as much as they help. The ingredients in home remedies are used in most good nail fungal treatment systems.

5: Nail Lacquers

Nail Lacquers work best in my mind. They are totally safe unless you have an allergy to some ingredient which will resolve when the product is discontinued.The product adheres to the nail and penetrates in most cases. This is essential for proper treatment. Some lacquers leave a thick coating and patients hate the shiny look. The one I find best is PediMD. This leaves a non-greasy non- visible look. It completely penetrates the nail and adheres to the nail bed and nail matrix. It can be used to prevent fungus as a base coat. PediMD has shown excellent clinical test result for treating fungus and can also be used to prevent fungus return after any form of treatment. It invisible and we have not seen any skin reaction from it.

I hope this article clears up some of the nail fungus treatment options for you. Be careful to check what you are getting and be sure to protect the nail after any form of treatment in order to prevent the return of nail fungus infection.




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